Elasticity difference detection of silicon models and biological tissue by spatial phase shifting endoscopic Electronic-Speckle-Pattern Interferometry

Spatial phase shifting endoscopic ESPI (sps endoscopic ESPI) is a method for quantitative detection of displacements and movements in technical and biological cavities. In combination with reproducible tissue stimulation sps endoscopic ESPI opens up new perspectives for biomedical applications e. g. for tumour recognition by the detection of elasticity differences of biological tissue. Investigations on silicone tissue models with areas of locally decreased elasticity by application of SPS endoscopic ESPI in combination with different methods of tissue stimulation have been carried out to determine the detection range of the method. Furthermore, an evaluation of parameters for tissue elasticity differentiation has been performed. Results of in vitro investigations on biological specimen demonstrate the applicability of the method.