Adaptive measurement systems using digital optical technologies

Recent advances in the control of light fields enable a paradigm shift of measurement systems. Using adaptive components, novel systems are designed for the systematic enhancement of computer-aided metrology. For biomedical applications the employment of electrically tunable lenses in 3D microscopy with structured illumination is outlined. Adaptive microscopy of zebrafish embryos with reporter gene-driven fluorescence in the thyroid gland is highlighted. We report on a contactless mechanical phenotyping. This is accomplished by taking advantage of Brillouin scattering and a virtually imaged phased array spectrometer. Exploiting scattering effects by time-reversal enables the transmission of structured light patterns through multimode fibers. The delivery of nearly diffraction-limited light into can be harnessed for optogenetics. The paradigm-shift to adaptive digital metrology by using programmable photonic devices will be highlighted.